Traditional lipid profiles often fail to detect small, dense LDL and IDL particles, which pose significant cardiovascular risks (1, 2). Elevated cholesterol levels do not consistently indicate the risk of heart attacks, as harmful LDL particles can exist even with normal cholesterol levels. In contrast, Liposcreen LDL Subfractions and Oxidised LDL (4031) panel offers a comprehensive analysis by quantifying all lipoprotein sub-fractions, distinguishing between less atherogenic LDL- 1 and LDL-2 and highly atherogenic LDL-3 to LDL-7, and measuring VLDL and IDL cholesterol (1,2).Understanding the type and size of cholesterol particles is crucial for precise risk assessment and treatment choices, particularly because small LDL particles are especially dangerous. This panel also includes Oxidized LDL and HDL subfractions. Oxidised LDL, which is a modified form of LDL cholesterol that has undergone oxidative damage, makes LDL particles a significant risk factor in the development of atherosclerosis (1). HDL subfractions encompass distinct subtypes of HDL, each equipped with unique attributes and functions in maintaining cardiovascular health (1,2). This panel offers a thorough evaluation of critical factors that impact both cardiovascular health and the risk of developing heart-related conditions.